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BLAST GENE THERAPY

Five longevity genes.

One non-viral delivery platform.

Blast Longevity develops and manufactures non-viral gene therapies for cellular repair, metabolic function, and vascular health : supplied to partner clinics and licensed physicians worldwide.

We do not treat patients. Tell us where you are and we can recommend a physician or partner clinic.

2008

Developing biologics since

Non-viral

Non-viral & non-integrating

Tested

Third-party tested

Global

Partner clinics worldwide

OUR PRODUCTS

The five gene therapies

Each construct targets a different pillar of healthy aging. Select one to request information, or ask an expert which fits your goals.

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Klotho

Klotho

ACTS SYSTEMICALLY

A protein produced mainly in the kidney and brain that declines steadily with age. Associated in the literature with cognitive performance, vascular integrity and renal function.

  • Cognitive resilience
  • Endothelial and vascular health
  • Mineral and bone regulation
  • Inflammatory balance
  • The high performer who wants to stay sharp, focused, and on top of their game
Follistatin

Follistatin

ACTS SYSTEMICALLY

Our construct expresses FST-344, the isoform that acts on skeletal muscle with minimal effect on other tissue, distinct from the hepatic form of follistatin.

Muscle has a built-in brake. A protein called myostatin tells muscle when to stop growing, and with age that signal increasingly outweighs the body's capacity to rebuild. Follistatin is its natural counterweight: it binds myostatin and eases the brake, so muscle can respond to training and repair.

  • Lean muscle mass
  • Recovery after exertion
  • Postural and core musculature
  • Resting metabolic rate
  • The athlete or bodybuilder chasing peak muscle performance
  • Anyone who wants to stay steady and strong on their feet, at any age
  • Faster recovery after exertion, whether you're 25 or 75
LAV-BPIFB4

LAV–BPIFB4

ACTS SYSTEMICALLY

A variant of the BPIFB4 gene carried at unusually high frequency by people who reach exceptional ages. Studied for effects on the blood vessel lining and on immune and vascular aging.

  • Endothelial function
  • Small vessel and cerebrovascular support
  • Immune and vascular aging
  • Inflammatory balance
  • Those focused on cardiovascular longevity and vascular health as they age
  • Best discussed with your physician if heart and vascular health is already a focus of your care
VEGF-A

VEGF-A

ACTS LOCALLY

Drives the formation of new capillaries. VEGF-A protein diffuses only a few centimeters from where it is placed, so it builds circulation precisely in the area a physician treats.

  • Scalp and hair
  • Skin and facial rejuvenation
  • Localized peripheral sites
  • Circulation-dependent goals
  • Those interested in aesthetics and early scalp or skin support
  • Those who want to address early thinning before it progresses
  • Also appropriate for facial and skin rejuvenation goals
FGF21

FGF21

ACTS SYSTEMICALLY

A hormone produced principally by the liver that helps govern how the body draws energy from fat and glucose. Studied for its role in insulin sensitivity and energy expenditure.

  • Insulin sensitivity
  • Fat and glucose metabolism
  • Brown adipose tissue activity
  • Hepatic metabolic support
  • Anyone juggling a full plate who wants sustainable, steady energy
  • Those focused on healthy metabolism as part of their daily routine
  • Those who feel the cold easily and want to support a balanced metabolism

What we do

We are a biotechnology company. We design, produce, and third-party test the gene therapy constructs, and we supply them to clinics and licensed physicians.

What we don't do

We don't diagnose, prescribe, or administer. A licensed physician decides whether a therapy is appropriate for you. If you don't have one, we can recommend a partner clinic or physician near you.

THE TECHNOLOGY

What Blast Gene Expression is

Gene expression technology gives your cells a set of instructions rather than a finished molecule. Instead of injecting a protein that clears within hours or days, a small closed ring of DNA is delivered into cells, which then produce the protein themselves.

Blast constructs are non-viral. They carry no viral vector and none of the bacterial backbone that plasmid constructs retain, and they remain outside the genome rather than integrating into your DNA. A single administration is designed to sustain elevated protein levels for up to twelve months, after which the effect fades unless it is repeated.

Five constructs are currently in distribution. They can be used individually or in combination, and a physician may pair them with complementary regenerative protocols depending on the goal.

Not sure which construct fits your goals?

IN PRACTICE

Used alone, or built into a program

Gene expression protocols can be used alone or integrated into a broader program. Some people come for a single construct with one goal in mind. Others work with a clinic on a program that combines several protocols with complementary regenerative and peptide therapies.

Brain enhancement
Metabolism reset
Muscle & joint optimization
Skin multimodal rejuvenation
Hair rejuvenation
Whole-body rejuvenation
Chronic condition resolution

GETTING STARTED

How to access these therapies

STEP 01

Tell us your goals

Our team explains what each construct does, what it doesn't do, and what the evidence currently supports.

STEP 02

We recommend a physician

We can point you to a partner clinic or licensed physician near you. You're equally welcome to bring your own doctor to us.

STEP 03

Your physician decides

They review your history and labs and determine which protocols, if any, are appropriate, and at what dose.

STEP 04

Administration & follow-up

Your physician administers and monitors. We supply the product and provide scientific support to their team.

ABOUT US

Why Blast Longevity

Founded and led by Dr. Brigitte Hanly, PhD, working in regenerative science and gene delivery since 2008. Our laboratory and headquarters are in Los Cabos, Mexico; our products go out to clinics worldwide.

  • Non-viral and non-integrating, with no bacterial backbone

  • Manufactured in-house and third-party tested for identity and purity

  • Supplied to a vetted network of partner clinics and physicians

  • Scientific rationale published openly through the Blast Journal

SEE THE SCIENCE

Inside the work

QUESTIONS

Frequently asked

Can you recommend a physician or clinic to me?

Yes. Tell us where you are and what you're interested in. Our network includes two affiliated clinics, Blast Institute in Los Cabos, with a second location opening in Cancún, as well as partner clinics and licensed physicians in other regions. The clinical relationship is between you and the physician you choose.

Can I bring this to my own doctor?

Often, yes. Physicians can register with us directly, and we provide the scientific documentation, handling requirements and protocol guidance their team needs. Availability depends on the regulations where they practice.

How long does one administration last?

Blast constructs are designed for sustained expression of up to twelve months from a single administration. The DNA does not integrate into the genome, so expression declines and the effect resolves rather than persisting indefinitely.

Can more than one therapy be combined?

Yes, and in practice they usually are. Combinations are a clinical decision made by the treating physician based on your goals, your labs and your history.

Which therapy applies to hair or skin?

VEGF-A. Because it builds capillary networks in the area where it is placed, it is the construct physicians use for the scalp and for facial work. Your physician will advise on what suits your case.

Get Started

Request product information

Tell us a little about what you're looking for.

If you need a physician, we'll include recommendations for clinics in your region.

Blast Longevity is a biotechnology company headquartered in Los Cabos, Mexico. We manufacture and distribute biologic products; we do not provide medical care, diagnosis or treatment, and nothing on this page is medical advice. Referrals to partner clinics and physicians are provided as a convenience. Whether any protocol is appropriate for an individual is determined solely by a licensed physician following a personal evaluation.

These products have not been evaluated or approved by the U.S. Food and Drug Administration or by any comparable regulatory authority, and are not intended to diagnose, treat, cure or prevent any disease. Availability varies by jurisdiction. Individual results vary.

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